Experience a weekend in vibrant Guadalajara with this comprehensive guide. Tour the impressive Historic Center with its majestic Cathedral, the Plaza de Armas, and the Government Palace with Jose Clemente Orozco's imposing murals. Visit the Cabañas Cultural Institute, a World Heritage Site, and explore the bustling San Juan de Dios Market. Don't miss the charming Tlaquepaque neighborhood with its galleries and crafts, and enjoy the authentic Tapatio experience with mariachis at Plaza de los Mariachis or El Parián. The guide offers detailed information on local gastronomy, such as tortas ahogadas and birria, transportation tips, and climatological data for each season.